Careers

Stem CentRx ™ is focused on scientific discovery and development of successful cancer drugs. We are funded by scientists and entrepreneurs with a long-term perspective on our business. Our culture is an apolitical meritocracy where performance and teamwork are rewarded. Stem CentRx has assembled a talented and motivated team, and is looking to recruit additional employees with world-class expertise in their practice, versatility to contribute broadly across the company, high energy and an entrepreneurial spirit.

Bioinformatics / IT - Bioinformatics Analyst

Description

As part of a talented and multi-disciplinary team advancing an exciting new approach to drug discovery and development, the successful candidate will be expected to contribute to the team by participating in the development of strategies and techniques for statistical analysis of expression data, pathways analysis, and potentially working closely with a biomarker/diagnostics scientist on related projects involving public and private clinical data. The ability to work independently, while effectively interacting and communicating with other team members, is also prerequisite. Consideration will be given to strong candidates with lesser experience.

Requirements:

1. A bioinformatics, biostatistics or related graduate degree
2. 2+ years of experience is preferred
3. Technical experience using/scripting in R/Biocondcutor, BioPerl or BioPython
4. Familiarity with command-line UNIX/Linux
5. Ability to multitask and work in a fast-paced environment
6. Motivated, organized and disciplined record keeping
7. Great personality and excellent communication skills
8. Strong track record of achievement and advancement desired

Bioinformatics / IT - Software Developer

Description

As part of a talented and multi-disciplinary team advancing an exciting new approach to drug discovery and development, the successful candidate will be expected to contribute to the team by participating in the development of custom web based software for use by scientists. The ability to work independently, while effectively interacting and communicating with other team members, is also prerequisite. Consideration will be given to strong candidates with lesser experience.

Requirements:

1. A computer science or related bachelor’s degree or1 year of experience
2. Technical experience in one of Ruby, RoR, Java, Grails
3. Experience working with Tableau is a plus
4. Experience with a code management system, preferably Git
5. Ability to multitask and work in a fast-paced environment
6. Motivated, organized and disciplined record keeping
7. Great personality and excellent communication skills
8. Strong track record of achievement and advancement desired

Cancer Biology - Research Associate / Sr. Research Associate

Description

As part of a talented and multi-disciplinary team advancing an exciting new approach to drug discovery and development, Stem CentRx is looking to hire a Research Associate or Senior Research Associate with experience in stem cell biology and oncology drug discovery. The successful candidate will work as part of a Team to leverage Stem CentRx’s assets to facilitate discovery and validation of cancer stem cell-associated therapeutic targets and develop circulating tumor cell-associated companion diagnostics in support of clinical drug candidates. The successful applicant will also be expected to introduce best practices from past experiences to enrich Stem CentRx’s scientific discovery and company culture.

The candidate must have a strong desire to work in a dynamic Team environment and aggressively contribute to the company’s growth and mission.

Requirements:

1. BS or equivalent degree in biology or a related field, with 3+ years of relevant academic and/or industry experience
2. Demonstrated skill at multicolor flow cytometry, RNA handling, and qRT-PCR
3. Experienced in tissue culture, cell based assays, and proficiency handling blood and working with small cell numbers desired
4. Ability to multitask and meet deadlines in a fast-paced environment
5. Motivated, proactive, organized, and disciplined at record keeping
6. Great personality and excellent communication skills are essential

Antibody Discovery - Sr. Research Associate / Associate Scientist / Scientist

Description

As part of a talented, multi-disciplinary and passionate team advancing an exciting new approach to drug discovery and development, we are looking for highly motivated candidates who will spearhead execution of therapeutic antibody generation using hybridoma and other related technologies in the Antibody Discovery group at Stem CentRx.

The ideal candidate would have hands-on experience across the broad spectrum of work involved, i.e. hybridoma technology, electrofusions, flow cytometry, single-cell cloning, antigen conjugations and cell biology assay development using automation.

This scientist will design immunization strategies for simple to highly complex targets, perform B-cell isolation, enrichment and fusions, in addition to devising and executing high-throughput automated screening approaches to select high quality drug candidates. The successful candidate should have the ability to integrate the requirements dictated by the biology of targets in the generation of antibody therapeutics and have considerable experience in troubleshooting issues arising during any phase of projects.

The scientist must be able to proactively communicate with cross-functional teams to obtain support for antibody therapeutic generation, antigen source or functional screening, and will be expected to stay on top of current trends in hybridoma processes so as to implement new processes and efficiencies if beneficial.

Requirements:

1. Our ideal candidate should have a Ph.D. with 0-2 years, MS or BS with 4-6 years of experience in Cellular Biology, Immunology, Biochemistry, or a related field, with at least 2 years of biotech experience in the therapeutic antibody generation field.
2. Must have hands-on in-depth experience in hybridoma technology and good understanding in basic immunology, molecular biology, and antibody discovery.
3. Significant knowledge and experience with high throughput screening assay development preferably utilizing Beckman, Hamilton or Tecan robotics. Experience with flow cytometry and ELISAs is highly preferred.
4. Experience with FACS sorting, antibody expression, antigen conjugations and purification is highly preferred.
5. Candidates should be detail-oriented, possess excellent organizational and communication skills, and able to multitask across several scientific areas. The candidate should be able to work as part of a team, while at the same time have the proven ability to independently plan and direct projects to completion within required timelines.

CV / Resume

hr@stemcentrx.com
Please include the group name in the subject line of the email so that your resume is forwarded properly to the hiring manager.

Current Open Positions:

Antibody Discovery
Sr. Research Associate / Associate Scientist / Scientist

Bioinformatics / IT
Bioinformatics Analyst
Software Developer

Cancer Biology
Research Associate / Sr. Research Associate